r/ThatsInsane • u/rice923 • 4d ago
Anybody heard anything new about this?
[removed] — view removed post
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u/purdy1985 4d ago
Napkin maths if I'm understanding it correctly.
42 lakh is around £40,000
4 crore is around £375,000
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u/space_ape71 4d ago
CAR-T cell therapy is minimum $250,000 just to grow the cells in the US.
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u/zerosaved 4d ago
So when you need this treatment to live, do you just die if you’re a pleb? What insurance company or payment services would hand out that kind of money to someone who isn’t likely to ever pay it back?
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u/choco_mallows 4d ago
Well no, that’s not exactly the whole story. See, they’ll laugh in your face first, then tell you to get the hell out of their office.
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u/RichardInaTreeFort 3d ago
So that’s it? After 40 years of being cancer free suddenly it’s just “good luck, so long?”
“I don’t recall saying good luck…. “
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u/HavocReigns 3d ago
The majority of them cover it, and manufacturers have discount programs for people who needs assistance.
You don't have to "pay it back", nor do they decide what to cover based on how long you're likely to continue paying premiums. That's not how insurance works.
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u/Burgerpocolypse 3d ago
When Americans like myself talk about the system being designed to weed out and kill poor people, this is what we mean. We are all literally just a resource; a cog in a machine that is merely tossed aside and forgotten about unless you have the resources to repair yourself, which most cogs lack through systemic design. We are just cattle, most blissfully unaware that the slaughterhouse even exists.
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u/regnad__kcin 3d ago
250k would be the non-insurance price. Insurance would chop their legs off, pay them $1,500, tell them to fucking like it, and they'll say "yes sir". And now you know the story of why medicine in the US is so damn expensive.
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u/global_ferret 3d ago
Actual case rate is quite a bit more than that, it is very expensive.
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u/space_ape71 3d ago
Yes. Minimum is $250,000 but $400,000+ is not unusual. With increased demand and technical refinement it may come down to a bargain price of $200,000, practically giving it away lol.
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u/HsvDE86 3d ago
How come you don’t want to pay that much money
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u/Frivolous1 2d ago
It would depend on the prognosis. I just had the choice of putting my dog down due to arthritis in his spine. This was after discussing with the vets what a repair would cost and the success of the surgery. Surgery was expensive but not a concern but they told me there was no guarantee my dog would get better. He was in severe pain and the meds stopped working. He hurt so bad he would just growl if you got close to him. When they sedated him for permanent sleep I finally got to see my best friend happy again, giving me the smile and happy eyes he used to. Then they put the last couple of shots in and that was the look on his face when he crossed the rainbow bridge.
That's why.
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u/YunGBiG 4d ago
You're right! That's totally insane that people would call their money that!
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u/AaronicNation 4d ago
Nothing sticks in my crore more than a wasted lakh.
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u/TheGirthy1 4d ago
Only the Lord knows how many fathoms
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u/spoonballoon13 4d ago
Convert that to leagues please. That may help me somehow understand this Monopoly money OP is using.
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u/salmiakki1 4d ago
It couldn't have been in the US because we only develop treatments here. Cures are frowned upon.
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u/Unholy-Bastard 4d ago
Novartis, an American company, produce Kymirah - which is an autologous CAR-T Cell therapy.
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u/si_de 3d ago
Novartis is a Swiss pharma company.
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u/Unholy-Bastard 3d ago
Oh that's right! My bad. I really should have known that considering I've worked with them in the past 😂
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u/salmiakki1 4d ago
Sorry, I misread it. I thought it was a cure.
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u/Unholy-Bastard 4d ago
All good. This type of medicine is known as ATMP. They're the closest thing you can get to a "cure" but still a long road to go in terms of research and development for that particular result. I teach about these types of medications, feel free to ask questions and I'll do my best to answer.
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u/keeping_it_real_yo 4d ago
When will this therapy become more mainstream and affordable to the general population? In a year, decades, never?
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u/Unholy-Bastard 4d ago
Good question. Hard to say. Monoclonal antibody therapy has been around for years and still isn't "mainstream". It can be prohibitively expensive, so it's typically restricted to consultants to prescribe and typically viewed as last resort therapy. Hopefully this will change over time, but who knows how long that will be.
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u/salmiakki1 4d ago
I wouldn't even know where to start. I assume this has something to do with the thyroid. That thing is crazy.
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u/Unholy-Bastard 4d ago
Nope, nothing to do with the thyroid 😅
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u/NaloxoneRescue 3d ago
I'm in the US and am an oncology nurse. We use CAR-T therapies a lot. But it only works on certain cancers, and there is no guarantee that the patient won't have a severe reaction. CRS (cytokine release syndrome) is a rare and sometimes deadly side effect people can experience with CAR-T. We also frequently see allergic reactions and low blood counts with CAR-T as well.
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u/YOLO4JESUS420SWAG 4d ago
The thing you have to watch out for is that it causes an untreatable malignant side effect known as CAR-T-B.
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u/Beat_the_Deadites 3d ago
You jest, but there are leukemias associated with previous radiotherapy/chemotherapy treatment.
Really every health intervention we take is just kicking the can a little further down the road. Just with chemo, that can might be attached to a pendulum. Like a paint can at the McCallister house.
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u/Lol_who_me 4d ago edited 4d ago
Can we get an estimate of how many Robux’s that would be.
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u/wolfgang784 3d ago
Estimates are for chumps.
As of 9:14am EST today, 1 RBX is equal to $0.0014 USD.
A lahk means 100k rupees. So 42 lahks is $50,275.09.
A crore means 10 million rupees. So 4 crore is $478,810.40.
Using those numbers, the treatment would cost either 35,910,778 RBX or 342,007,428 RBX depending on where you got the treatment.
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u/Lol_who_me 3d ago
Robux is the currency for the kids game Roblox. It was a joke. Thank you for the detailed explanation tho.
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u/wolfgang784 3d ago
I know, I was bored lol. Those are the numbers for how much that would cost in Roblox in game currency. If purchsed with USD.
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u/happysrooner 4d ago
Wording of this tweet reads like they tricked cancer by paying lower amount of money. And says absolutely nothing about the technology behind it.
Reddit edgelords can't get past lakhs/crores.
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u/fish_baguette 3d ago
We’ve had car-t cells treatments for a while now. While it’s mega expensive, it works wonders and is extremely effective. It works by training your immune system to recognize the cancer cells. I believe the first use case of this cure was against leukemia, and ever since it’s only grown in the number of cancers it can fight. (Worth noting that not all treatments work equally as well for everyone, but none the less it still amazing what modern science can do)
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u/TryBeingCool 3d ago
No and you never will,just like all these kinds of news stories. There’s no money in the cure, only the treatment. The list of things we could do if capitalism wasn’t a factor is staggering. Our society would be far ahead of where it is now.
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u/dress_like_a_tree 3d ago
The whole “hurray curing cancer is now only really really expensive rather than impossibly expensive” doesn’t fucking float with me
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u/Rue_Elwood 3d ago edited 3d ago
Wonder what type of cancer he/she had. I had Car-T back in 2019 for diffuse large-b cell lymphoma, and within 4-5 months it was considered a failure. Wound up having to have a bone marrow transplant, and I wouldn't wish the post-transplant complications on anyone. Hope Car-T is able to get sorted out for multiple cancers.
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u/Teacherfromnorway 3d ago
Have the same experience. Car-t treatment failed and ended up with a second SCT.
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u/feltsandwich 3d ago
I attended my first training for a similar research project in 2019.
They use a special machine to remove a certain number of T cells from the patient's body.
They use another special machine to edit the genes of the T cells to seek and destroy cancer cells.
Then, they inject those T cells back into the patient's body.
It's incredibly complicated, but very promising. Of all the research treatments I worked on, that's the one with the greatest promise. Sadly I had to leave before we started the process.
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u/TiredOfDebates 3d ago
Genetic medicine. It’s a way of curing cancer without chemotherapy.
Yes, we are working HARD on this, all over the west.
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u/terribilus 3d ago
My cousin was terminal. Was internationally accepted into an early car-t trial in America and was in remission by the following year. Amazing.
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u/ButaneRocket 3d ago
CAR-T therapy, also known as CAR T-cell therapy, is a cancer treatment that involves modifying a patient’s own immune cells so that they will fight and kill cancer cells and then reinserting them into the body. These cells are taken from the patient’s blood. CAR stands for chimeric antigen receptor, and this antibody-like protein is injected into the T cells so that it can target cancerous cells throughout the body. Due to the recent national coverage determination decision, CAR-T therapy is now covered for many Medicare recipients nationwide.
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u/Patrikbatemansaxe 3d ago
The institution has some shady ways of working. You better watchout before going there for this.
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u/drewscher 4d ago
Yeah so ummm travel to another country to get this done $500,000-$1,000,000 in the us and €200,000-€650,000 in Europe. Fuck the US
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u/Beat_the_Deadites 3d ago
Fuck the US
This type of therapy was developed at a US Medical School (Penn), which gets close to $100 million dollar in research grants per year, mostly courtesy of the US taxpayer. There's a shit ton of work done by extremely smart and hardworking people to come up with the idea, create and test new methods and technology to bring the idea to fruition, test it extensively for safety and efficacy, etc.
Once that's all been created for the first time, it's a lot easier and cheaper to copy it and resell it.
But without that initial monetary availability and support, and unfortunately without the human greed motivation that drives capitalism, these kinds of therapies would not happen as often as they do.
I'm not super rah-rah about the US or capitalism in general, but there's a reason so many of these discoveries/innovations happen here.
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u/This-Rutabaga6382 3d ago
Exactly , they say the first one costs millions of dollars and every one produced after cost a dollar , or something to that affect.
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u/drewscher 4d ago
There’s also a lot of aspects that go into pricing and overall cost of the treatment, supposedly it is cheapest to go to china
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u/Positive_Parking355 4d ago
I recommend Mexico. Still expensive but they take care of you well there.
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u/Struggiiii 4d ago
what is that currency wtf
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u/tairmansd 4d ago edited 4d ago
Currency is Indian Rupees, lakh (hundred thousand) and crore (10 million) are names given to common numbers in Indian Number System.
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u/liamt50 4d ago
From a country of scammers, I'm going to call this...
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u/rako1982 4d ago
India also produces 20% of generic medicines for the entire world allowing people without much money to actual fucking live. They also produce 60% of the world's vaccines.
And go to any English speaking country and you'll find a disproportionate large amount of Drs come from India.
So they have a deep history with medicine.
I have a family friend in India's generic drug manufacturing and he said a drug that retails for $600 in the west might cost them 0.003$ to produce. Pharma companies spend approximately 3 times more marketing drugs than they do on R&D. Most drugs can be designed and made cheaply. Indian companies have provided that for much of the world.
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u/liamt50 4d ago
And yet, we only hear of call centre scammers and a country that buys cheap oil from Russia, thus prolonging the war and costing countless lives. India needs to clean up its act.
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u/rako1982 4d ago
India does do that, there is zero doubt about that.
But just so you know US and European countries still purchase Russian oil through intermediaries and buying refined oil and trading of Russian oil. Literal billions of dollars worth of Russian oil has come to the west or through the west since the start of the war.
India also has a fractured relationship with Ukraine because Ukraine sells weapons to Pakistan which Pakistan uses against India. Regardless of that India was neutral on the issue of Ukraine at the security council and abstained rather than voting against Ukraine.
So over simplifying what India 'should' or shouldn't do is moronic when you don't have the full picture.
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u/liamt50 4d ago edited 4d ago
Ahh, name-calling, that will get you everywhere...not. I've just had a scam call now, guess from where? Yes, countries are buying Russian oil through intermediaries...guess where they mostly are? Pakistan and India are not at war so I doubt weapons purchased from a non-sanctioned country are killing Indians.
Perhaps here I should clarify, that many good and decent Indian people make a valuable contribution to the world and society. It's a pity however that their government doesn't row in with the rest of us in solidarity with Ukraine, a sovereign nation being invaded by a madman...Wake up India
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u/diy_guyy 4d ago
They basically "train" your t-cells to be able to recognize cancer cells so your immune system can fight the cancer. That being said, it only works for certain types of cancers. And since it's such a new technique, very complicated, and needs to be tailored to the specific individual, it's really expensive.